Megan Pennington, BSc, CLT
Scientific Research
The following is a curated library of scientific references demonstrating the connection between immune mediator release — inflammation — and a wide range of acute and chronic health conditions.
By identifying and removing the elements that trigger this response (reactive foods and other stressors), the body is able to self-regulate and repair. This is a cornerstone of every program and protocol at MP Integrative Health.
General: The Role of Mediators & Inflammation in Chronic Disease
Foundational research on immune activation and inflammatory mechanisms
- MRT Lab and Research — nowleap.com/research/PublicationsResearch
- The Clinical Use of Mediator Release Test in Food Sensitivity — Semantic Scholar
- Hypersensitivity Reactions — Cleveland Clinic
- Inflammation as a Key Player in All Diseases — meganpennington.com
- Inflammation, Disease & Diet — Harvard Magazine
- Chronic Inflammation in the Etiology of Disease — Nature Medicine
- Inflammation and Chronic Disease — NCBI PMC3492709
- Inflammation Research — Science Daily / PNAS
- Mediator Release and Immune Activation — NCBI PMC6996528
- Journal of Immunology Research 2018 — Hindawi
- Food Hypersensitivity and Delayed Reactions — Wiley Online Library
- Inflammation Mechanisms — NCBI PMC4579563
Specific Conditions: The Role of Inflammation
Peer-reviewed research linking inflammatory mediator release to specific diagnoses
Acne
2 refsAging
1 refAllergies
1 refALS
1 refAlzheimer's Disease
1 refAnxiety
3 refsArthritis
2 refsAutism
6 refsAutoimmune Disease
2 refsBipolar Disorder
1 refBloating
1 refBlood Pressure
1 refBrain Fog
2 refsBreast Cancer
4 refsBurnout
1 refCancer (General)
2 refsCandida
1 refCardiovascular Disease
1 refCeliac Disease
2 refsCholesterol
3 refsCongestion / Sinusitis
1 refConstipation
1 refCoronary Artery Disease
1 refDepression
5 refsDiabetes Type 1
2 refsDiabetes Type 2 & General
3 refsDiarrhea
2 refsDysbiosis
2 refsEndometriosis
2 refsFatigue
2 refsFertility
2 refsFibroids
3 refsFibromyalgia
3 refsGallstones
1 refGastritis
1 refGERD / Heartburn / Reflux
2 refsGI Issues (General)
1 refGraves' Disease
2 refsHashimoto's / Thyroiditis
3 refsHeadaches
1 refHearing Loss
1 refHives (Urticaria)
2 refsHormones / Endocrine
1 refHot Flashes
1 refIBD / Crohn's / Ulcerative Colitis
3 refsIBS
2 refsInfection / Immunity
1 refInsomnia
2 refsInsulin Resistance
4 refsInterstitial Cystitis
2 refsLeukemia
1 refLong COVID / Post-Viral Fatigue
2 refsLung Cancer
1 refLupus (SLE)
2 refsMCAS (Mast Cell Activation Syndrome)
2 refsME/CFS (Chronic Fatigue Syndrome)
2 refsMenopause
1 refMental Health (General)
1 refMultiple Sclerosis
2 refsNeuropathy
2 refsNutrient Imbalance
1 refOsteoarthritis
3 refsOsteoporosis
1 refPain (General)
2 refsParkinson's Disease
2 refsPCOS
2 refsPostpartum Anxiety / Depression
1 refPOTS
1 refProstate / PSA
2 refsPsoriasis / Eczema
2 refsRaynaud's Syndrome
1 refRheumatoid Arthritis
2 refsRosacea
2 refsSjögren's
1 refSkin Disorders (General)
1 refSleep Apnea
1 refSpinal Injury
1 refStroke
1 refThyroid Nodules
1 refWeight Gain
1 refStress & Emotions: Their Role in Health
Research on how psychological stress and emotional state drive physical inflammation and disease
All Diseases
1 refAllergies
1 refAutoimmune Disease
1 refCancer
1 refCardiovascular Disease
1 refGut Issues
1 refHeadache
1 refHeartburn
1 refImmune System
1 refInflammation & Disease
1 refInsomnia
1 refPain
1 refSkin Conditions
1 refWeight Gain
1 refThis research supports what we see every day in clinical practice.
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